Comparison · Ergonomic mice

Compare Ergonomic Mice

Compare our ergonomic mice side by side — sizes, hand options and connection types — so you can find the right fit for your hand and your work.

By the No More Pain Ergonomics team · Australian ergonomic specialists since 2013 · Updated November 2026

Quick answer

Pick the size group that matches your hand, then compare. Most people start with a vertical mouse: the Ergo Comfi or Delux Mini for small hands, the Ease or Delux Medium X for medium hands, and the ComfortGrip or ErgoFeel for large hands. Choose a roller mouse for shoulder pain or to use either hand.

In this guide

Small hands
Medium hands
Large hands
Specialised designs
Most popular picks

Small hands

Mouse	Hand size	Hand	W × L × H	Connection
Ergo Comfi Mouse	Small	Right	7.5 cm × 10.5 cm × 6.5 cm	Wireless USB
Delux Mini Vertical Ergonomic Mouse	Small	Right	8.9 cm × 10.3 cm × 6.9 cm	Bluetooth + Wireless USB
Evoluent VMR4 Small	Small	Right	8.5 cm × 10.5 cm × 7.4 cm	Wireless USB + Wired USB
Elevate Vertical Ergonomic Mouse - White	Small–medium	Right	See product page	Bluetooth + Wireless USB

Medium hands

Mouse	Hand size	Hand	W × L × H	Connection
Ease Vertical Ergonomic Mouse	Medium	Left or right	5.7 cm × 11.5 cm × 8.7 cm	Wireless USB
Delux Medium X Vertical Ergonomic Mouse	Medium	Right	7.5 cm × 11.5 cm × 8 cm	Wireless USB
Jomaa Vertical Ergonomic Mouse	Medium	Right	See product page	Bluetooth + Wireless USB
ErgoFeel Pro Vertical Ergonomic Mouse	Medium–large	Right	8 cm × 10.5 cm × 8 cm	Bluetooth + Wireless USB
X-45 Vertical Ergonomic Mouse	Medium–large	Right	See product page	Bluetooth + Wireless USB

Large hands

Mouse	Hand size	Hand	W × L × H	Connection
ComfortGrip Vertical Ergonomic Mouse	Medium–large	Right	9 cm × 11 cm × 10 cm	Bluetooth + Wireless USB
ErgoFeel Vertical Ergonomic Mouse	Large	Left or right	7 cm × 12 cm × 7 cm	Wireless USB + Wired USB
Evoluent VMR4	Medium–large	Right	7.6 cm × 11.7 cm × 7.6 cm	Wireless USB + Wired USB
Evoluent VML4	Medium–large	Left	8.9 cm × 11.1 cm × 8 cm	Wired USB
Jomaa Ergonomic Trackball Vertical Mouse	Large	Right	9.2 cm × 11.5 cm × 7.1 cm	Bluetooth + Wireless USB

Specialised designs

Mouse	Type	Hand	Best for	Connection
ErgoSlider Plus+ Mouse	Centred roller	Either	Shoulder pain; no gripping	Wired USB
RollerMouse Pro 3	Centred roller	Either	Shoulder, neck and wrist strain	Wired USB
HandshoeMouse Shift Ambidextrous Mouse	Contoured palm	Left or right	Whole-hand support	Bluetooth
OrthoMouse	Adjustable 45°	Right	Carpal tunnel	Wired USB
Unimouse	Adjustable tilt	Right	Power users, RSI prevention	Wireless USB + Wired USB
DXT Vertical Ergonomic Mouse	Pen-grip vertical	Either	Precision control	Wireless USB + Wired USB

Sizes are approximate. Check each product page for full specifications.

Most popular picks

Ease Vertical Ergonomic MouseBest for: Medium-hand users seeking ergonomic pain reliefView product

Ergo Comfi MouseBest for: Small-hand users seeking everyday pain reliefView product

ComfortGrip Vertical Ergonomic MouseBest for: Medium–large hands needing all-day comfortView product

ErgoSlider Plus+ MouseBest for: Left and right-handed users wanting minimal reachView product

Shop all ergonomic mice

Frequently asked questions

Which ergonomic mouse should I choose?

Start with your hand size, then your symptoms. Vertical mice suit most wrist and forearm complaints; roller mice suit shoulder pain and people who want to use either hand.

Do you have left-handed ergonomic mice?

Yes — including the Ease, ErgoFeel and Evoluent VML4, plus ambidextrous roller and contoured mice.

Wireless or wired?

Wireless is tidier and more flexible; Bluetooth + USB models switch between devices. Wired mice never need charging and suit shared or locked-down computers.

Related guides

No More Pain Ergonomics · nomorepainergonomics.com.au/pages/compare-ergonomic-mice · 1300 898 965 · info@nomorepainergonomics.com.au · Updated November 2026

Questions? We're here to help

Our ergonomic team can help with product advice, orders and anything else you need.

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Sturdy

Sturdy, non slip and the adjustable settings are so easy to manoeuvre. Excellent product and very happy with the purchase.

Hi Fran, thanks so much for the lovely review! We’re delighted you’re happy with your footrest and find it sturdy, non-slip, and easy to adjust.

Great ergonomic mouse

Great ergonomic mouse, not too big and is easy to use. It didn't take long at all to get use to the different hand position.

Hi! We're thrilled to hear you're enjoying the Ergo Comfi Mouse and finding it easy to use. Thanks for sharing your positive experience! 😊

Good quality

Good quality, durable and perfect for my home corner office space

Hi, we're thrilled to hear you're happy with the desk! Thanks for sharing your experience. 😊

I like this cushion

I like this cushion. When I unwrapped it I thought the holes for the ishiums were too far apart but they’re pretty good and overall the cushion has relieved the pain I was experiencing while driving my car to a large extent. Very pleased

Hi Randy, we're glad to hear the cushion is helping and that you're pleased with it! Thanks for sharing your experience. 😊

Fantastic support

Fantastic support. Tried a cheaper variety which was no good. Highly recommend No More Pain.

Hi Carol, we're thrilled to hear you're happy with your support cushion! Thank you for recommending No More Pain Ergonomics. We appreciate your trust and support!

Nice and comfortable

Nice and comfortable, only thing i can say negative is that it sits a bit high in the car.

We're glad to hear you're comfortable with the cushion. If the height feels too high, we recommend trying to adjust your seat or position for better comfort. Thanks for your feedback! 😊